Because of the long distances between churches, which could be over a hundred miles between the farthest churches, regionalization of churches was implemented. The Diocese has been divided into four regions – North, South, East and West in Southern California and one region in Hawaii. This makes coordination of services, regional meetings among local priests, deacons, and Sunday School teachers, more feasible and practical. Also, services such as retreats and other activities can be combined.
The first church acquired by newly immigrant Copts to Southern California was St. Mark in Los Angeles. The number of churches has steadily grown, as reflected in the following list.
Eastern Region
9 Parishes Serving the Inland Empire and Surrounding Areas
| St. Abanoub and St. Antony Coptic Orthodox Church Norco, CA | St. George the New Martyr Coptic Orthodox Church Hemet, CA |
| St. John Coptic Orthodox Church Covina, CA | St. Justina Coptic Orthodox Church Rancho Cucamonga, CA |
| St. Mary Coptic Orthodox Church Victorville, CA | St. Mary Magdalene Coptic Orthodox Church Palm Springs, CA |
| St. Maurice and St. Verena Coptic Village Retreat Center Big Bear Lake, CA | St. Maurice Coptic Orthodox Church Pomona, CA |
| St. Mina Coptic Orthodox Church Colton, CA |
Western Region
6 Parishes Serving Los Angeles and Surrounding Areas
| Holy Virgin Mary and Saint Pishoy Coptic Orthodox Church Los Angeles, CA | St. Bishoy and St. Paul Coptic Orthodox Church Los Angeles, CA |
| St. Cyril of Alexandria Coptic Orthodox Church El Monte, CA | St. Mark Coptic Orthodox Church (LA) Los Angeles |
| St. Mercurious and St. Abraam Coptic Orthodox Church Torrance, CA | St. Peter and St. Paul Coptic Orthodox Church Santa Monica, CA |
Northern Region
8 Parishes Serving the San Fernando Valley and Surrounding Areas
| Archangel Michael Coptic Orthodox Church (SV) Simi Valley, CA | Archangel Raphael and St. Mina Coptic Orthodox Church Palmdale, CA |
| Church of the Three Abba Makari Santa Maria, CA | St. Demiana Coptic Orthodox Church Bakersfield, CA |
| St. George and St. Bishoy Coptic Orthodox Church Visalia, CA | St. John the Baptist Coptic Orthodox Church Oxnard, CA |
| St. Mary and St. Athanasius Coptic Orthodox Church Northridge, CA | St. Mary of Egypt Coptic Orthodox Church Newhall, CA |
Southern Region
8 Parishes Serving Orange County and Surrounding Areas
| Archangel Michael Coptic Orthodox Church (OC) Santa Ana, CA | St. Demiana Coptic Orthodox Church San Diego, CA |
| St. George Coptic Orthodox Church Bellflower, CA | St. Marina Coptic Orthodox Church Irvine, CA |
| St. Mary and St. Verena Coptic Orthodox Church Anaheim, CA | St. Paul American Coptic Orthodox Church Tustin, CA |
| St. Thomas the Hermit Coptic Orthodox Church Temecula, CA | St. Verena and the Three Holy Youth Coptic Orthodox Church Orange, CA |
Hawaii Region
1 Parish Serving Hawaii and Her Islands
| St. Mark Coptic Orthodox Church (HI) Honolulu, HI |






